In 1975, a gift from the late Jane Bancroft Steele Cook established the Edwin L. Steele Laboratory for Tumor Biology. Named in memory of her husband, the Steele Laboratory is a world leader in quantitative tumor pathophysiology. This early investment in cancer research at Mass General has provided a solid foundation for today’s research discoveries and treatments. Key achievements of the Steele Laboratory include the development of sophisticated animal models and innovative imaging technology to reveal the inner workings of solid tumors; the translation of pre-clinical findings to patients, including brain and colorectal cancer patients; and the training of more than 200 physicians and scientists, many of whom have gone on to become world leaders in their areas of expertise.
Under the direction of Rakesh K. Jain, PhD, Steele Laboatory researchers are dedicated to improving the prevention, detection and treatment of cancer through a better understanding of tumor pathophysiology and host-tumor interactions. Their research is working to overcome vascular, interstitial and cellular barriers to molecular medicines that advance detection and treatment of primary and metastatic tumors, and translating these strategies from bench to bedside.
Jane also endowed the Andrew Werk Cook Professorship of Tumor Biology, currently held by Dr. Jain.
